Deciding Between Novel, Nonstatin Therapies
May 19th 2025Panelists discuss how medical professionals consider PCSK9 inhibitors, bempedoic acid, and inclisiran in various clinical scenarios, their experiences with these newer therapies, the implications of the INCEPTION trial for treating patients with high-risk cardiovascular disease—particularly those who are statin-intolerant—the urgency of postcoronary event treatment, and emerging data on the broader impact of low-density lipoprotein cholesterol (LDL-C)–lowering therapies on quality of life.
Balancing Treatment and Quality of Life: Adverse Events of First-Line Agents in NSCLC
May 16th 2025A panelist discusses how EGFR tyrosine kinase inhibitors (TKIs) commonly cause dermatologic toxicities (including acneiform rash, dry skin, photosensitivity, and paronychia) and diarrhea, which can significantly impact patients’ quality of life by causing physical discomfort, affecting appearance, and limiting daily activities.
AAN 2025: Patient Voices Key to Understanding Broader Benefits of Xywav in Sleep Disorders
May 15th 2025Logan Schneider, MD, highlights the importance of integrating patient-reported outcomes into clinical trials to better capture the full therapeutic impact of low-sodium oxybate (Xywav) beyond traditional sleep metrics.
The Role of Community Pharmacists in RSV Vaccine Uptake
May 12th 2025A panelist discusses how physicians can collaborate with community pharmacists to enhance respiratory syncytial virus (RSV) vaccine uptake by leveraging pharmacists' expertise in patient education, addressing vaccine hesitancy through empathetic communication, and emphasizing the safety, benefits, and risks of RSV vaccination.
Clinical Value of Nonstatin Therapies
May 12th 2025Panelists discuss how evidence from a value-based care perspective demonstrates long-term health benefits, including reduced recurrent events and hospitalizations, as well as cost savings associated with intensive low-density lipoprotein cholesterol (LDL-C)–lowering therapies beyond statins in patients who are very high-risk post-atherosclerotic cardiovascular disease (ASCVD), while also addressing key challenges health care providers face in selecting nonstatin therapies and strategies to overcome them.
Breaking New Ground: Emerging Therapies for Treatment of EGFR-Positive NSCLC
May 9th 2025A panelist discusses how emerging advancements in non–small cell lung cancer (NSCLC) treatment include the anticipated FDA approval of subcutaneous amivantamab, which would significantly reduce infusion-related reactions seen in the MARIPOSA trials while improving patient experience and reducing infusion center chair time, as well as promising antibody-drug conjugates like sacituzumab govitecan (Trodelvy) that may provide better first and second-line treatment options with potentially less toxicity than current standard regimens.
Identifying Candidates for RSV Vaccination
May 5th 2025A panelist discusses how physicians can partner with pharmacists to identify respiratory syncytial virus (RSV) vaccine candidates among high-risk populations, emphasizing the pharmacist’s role in prevention efforts and the importance of supportive care and awareness of newly approved vaccines and monoclonal antibodies.
The Impact of Respiratory Syncytial Virus (RSV) on Vulnerable Populations
May 5th 2025A panelist discusses how physicians can recognize the burden of RSV in high-risk populations, stay informed about preventive strategies such as vaccines and monoclonal antibodies, and apply clinical insights to reduce severe outcomes and hospitalizations.
Mechanisms of Action of Nonstatin Therapies
May 5th 2025Panelists discuss how PCSK9 inhibitors, bempedoic acid, and inclisiran lower low-density lipoprotein cholesterol (LDL-C) through distinct mechanisms—PCSK9 inhibitors enhance LDL receptor recycling, bempedoic acid inhibits ATP citrate lyase to reduce cholesterol synthesis, and inclisiran uses RNA interference to decrease PCSK9 production—comparing their efficacy in reducing recurrent cardiovascular events.
Effective Approaches for Utilizing Nonstatin Therapies
May 5th 2025Panelists discuss how medical professionals navigate statin initiation, considering contraindications or delays in specific patient populations, including those with liver disease or renal impairment, older adults, and other high-risk groups, while also examining evolving treatment patterns and factors influencing the adoption of more intensive low-density lipoprotein cholesterol (LDL-C)–lowering therapies.
Real-World Data, Real-Time Decisions: AI at the Front Lines of Oncology
May 2nd 2025Ravi Parikh, MD, MPP, FACP, discusses how artificial intelligence is transforming oncology pharmacy by accelerating drug development, enhancing clinical decision-making, supporting value-based care, and raising critical questions about ethics, regulation, and data integrity.
Enhancing Patient Care Through Multidisciplinary Team Collaboration in Management of NSCLC
May 2nd 2025A panelist discusses how pharmacists contribute to multidisciplinary care for patients with non–small cell lung cancer (NSCLC) by providing comprehensive education, creating customized medication calendars, ensuring appropriate dose adjustments for individual patient factors, advocating for patients to balance efficacy with toxicity management, and helping patients navigate insurance systems to access expensive medications through assistance programs, particularly when transitioning from targeted therapies to more complex regimens.
Barriers to Bridging Clinical Trial Data to Routine Pharmacy Practice
May 2nd 2025A panelist discusses how implementing new clinical trial findings into practice involves multiple challenges including operationalizing treatment regimens in electronic medical records (EMR), procuring medications, obtaining formal approval through institutional committees, and, most significantly, securing insurance approval since insurers often update their formularies less frequently than FDA approvals occur, which can delay patient care.
Precision Oncology in Focus: ctDNA's Role in Colon Cancer Management
April 30th 2025Sasha Watson, PharmD, BCOP, discusses the emerging role of circulating tumor DNA (ctDNA) in colon cancer, highlighting its potential to enhance precision oncology by improving early detection, guiding adjuvant therapy decisions, and monitoring disease recurrence and treatment resistance.