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Pembrolizumab demonstrated a statistically significant improvement in disease-free survival, reducing the risk of disease recurrence or death by 32% compared to placebo.

Molnupiravir (Lagevrio) is a potent ribonucleoside analog that blocks SARS-CoV-2 replication by acting as a competitive substrate of virally-encoded RNA-dependent RNA polymerase.

Treatment for endometrial cancer includes surgery, radiation therapy, chemotherapy, immunotherapy, and supportive care.

Pharmacists should keep an eye on the pipeline for autologous and allogeneic CAR T-cell therapies as well as antibody-specific treatments.

Facilities play key role in health care because of their bulk production, stringent quality standards and wide distribution.

Receipt of PrEP education or prescription relies heavily on a provider’s discretion, which can be subject to social biases.

Discontinued fentanyl infusion left attached to patient contributes to his death, but risk-reduction strategies can prevent similar mistakes.

Practicing mindfulness was associated with fewer psychological symptoms, such as posttraumatic stress, depression, and anxiety.

The panel also recommends considering risk factors for poor response, including uncontrolled disease, immunoparesis, the number of previous lines of therapy, and patient age.

In the IMPACT trial, women who were positive for high-risk HPV received a follow-up triage test to help determine whether their cervical cells were transforming to cervical pre-cancer.

The FDA initially approved regorafenib for chemorefractory metastatic colorectal cancer and unresectable gastrointestinal stromal tumor in 2012.

In addition to escalating workloads, the COVID-19 pandemic has exposed understaffing in the pharmacy profession.

Duration of therapy may be just 5 to 6 days for patients without risk factors for complications.

Sacituzumab govitecan-hziy is indicated for the treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer who have received 2 or more prior systemic therapies, at least 1 of which for metastatic disease.

Bladder cancer most often begins in the cells that line the inside of the bladder.

CMS Interim Final Rule on mandatory COVID-19 vaccinations for all facilities participating in Medicare and Medicaid potentially impacts pharmacies that provide services under a contract or arrangement with these facilities.

Pharmacy performance measures can support greater patient access to care and services through team-based care and to facilitate value-based contracts between pharmacists and payers.

It was previously known that beta-lactam antibiotics function by restricting cell wall growth, but the exact mechanics have remained unknown until now.

Odevixibat is indicated for the treatment of pruritus in patients 3 months of age and older with progressive familial intrahepatic cholestasis.

Risk factors for liver cancer include chronic infection with hepatitis B or hepatitis C virus, cirrhosis, diabetes, and non-alcoholic fatty liver disease.

Addressing barriers such as cognitive impairment, cultural issues, and denial can help patients avoid adverse effects.

The results were presented at the American Society of Nephrology Kidney Week 2021.

If authorized, ritonavir could be prescribed broadly as an at-home treatment to help reduce COVID-19 severity, hospitalizations, and deaths, as well as to reduce the probability of infection following exposure among adults.

Kymriah is a CD19-directed genetically modified autologous T-cell immunotherapy.

Heart defects associated with Eisenmenger syndrome cause blood to circulate abnormally in the heart and lungs.

Gaby Gabriel, MD, program director, interventional radiology residency and assistant program director, diagnostic radiology residency, University of Kentucky, discusses the implications of research into the treatment of liver metastases in patients with gastrointestinal NETs.

No new safety concerns were encountered, which the investigators said support the frontline use of daratumumab plus lenalidomide and dexamethasone for patients with multiple myeloma who are ineligible for transplantation.

Kyle Detwiler, CEO of Clever Leaves, discusses his company’s donation of $1 million in medical-grade cannabis to research organizations for the purposes of advancing medical research.

Gaby Gabriel, MD, program director, interventional radiology residency and assistant program director, diagnostic radiology residency, University of Kentucky, discusses the findings regarding the efficacy of combining and sequencing liver-directed therapy with systemic therapy.

Trends to watch include increased spending on drugs and treatments, expansion of pharmacists' role, and ongoing interest in home infusion therapy.