Hospital

A generic TDF/FTC costs as low as $30 per month, compared with about $1800 per month for branded TAF/FTC

Study examines whether dapagliflozin is cost-effective when added to standard of care for patients who have heart failure with reduced ejection fraction.

According to the investigators, the findings demonstrate that a 5-day regimen of stereotactic body radiotherapy, a form of external beam radiation therapy that uses a higher dose of radiation, had a 4-year cure rate of 82%.

Although there was a numerical difference between the mean number of new or newly enlarging T2 hyperintense lesions at week 72 of 0.05 (Q4W) and 0.20 (Q6W), this difference was not clinically meaningful in the context of the full data, according to the investigators.

ACE inhibitors are currently prescribed more commonly than ARBs as a first-time blood pressure control medicine despite this difference in AEs, the study authors noted.

According to a press release from Roche, the FDA is reviewing the company’s Biologics License Application under the Real-Time Oncology Review pilot program, which aims to explore a more efficient review process to ensure safe and effective treatments are available to patients as early as possible.

This month, I thought it would be beneficial to share a handful of examples from among the many Next Generation Pharmacist-nominated candidates.

MDM2 inhibitors and BET inhibitors, which show limited efficacy against acute myeloid leukemia (AML) as monotherapies, are potent against AML when used in combination, according to a study published in Nature Communications.

The OVATION 2 study combines GEN-1 with standard-of-care neoadjuvant chemotherapy (NACT) in patients newly diagnosed with stage 3 and 4 ovarian cancer.

Anna Legreid Dopp, PharmD, CPHQ, senior director of clinical guidelines and quality improvement at ASHP, said their organization was proud to sign onto a recent statement urging health care organizations to mandate COVID-19 vaccines for their employees.

The investigators also predicted that the increase in indications of novel diabetes treatments and their increased use is likely to result in greater expense.

Pharmacy Times interviewed Craig Freyer, PharmD, BCOP, and Andrew Lin, PharmD, BCOP, to discuss how to manage the logistical challenges that arise during the administration of CAR T therapy in inpatient and outpatient settings for patients with multiple myeloma.

The analysis used AstraZeneca’s global safety database, which contains all spontaneously reported adverse events from real-world use of its medicines and vaccines worldwide.

In addition to getting outside and taking time to enjoy hobbies outside of work, Carroll urged pharmacists to enjoy time with family and friends whenever possible.

The investigators noted that the levels of islatravir in peripheral blood mononuclear cells remained above the efficacy pharmacokinetics threshold for PrEP for both doses studied (60 mg and 120 mg) for 8 weeks following the last study dose.

Selexipag tablets were first approved by the FDA in 2015 to delay disease progression and reduce the risk of hospitalization for PAH.

The study demonstrated robust time and dose-dependent lowering of tau protein in cerebrospinal fluid (CSF) over the course of the 3-month treatment period.

Investigators estimated that globally, 4.1% of all new cancer diagnoses in 2020 were attributable to alcohol consumption.

On average, those who received a flu-like diagnosis changed their cell phone usage behavior 1 day before their diagnosis and the 2 to 4 days afterward.

A decrease in cancer-associated macrophage-like cells was associated with an approximately 300% increase in mean progression-free survival.

Insulin glargine-yfgn is the first interchangeable biosimilar product for the treatment of diabetes approved in the United States, which can provide patients with alternative, equally effective options for treating diabetes that could be more cost effective.

Workflow in the clinic and the pharmacy are critical for the implementation of a new and novel medication therapy, such as cabotegravir-rilpivirine.

Chad Hatfield, PharmD, MHA, BCPS, chief pharmacy officer at UC Davis Medical Center, discusses how data points used in oncology pharmacy practice and how it is collected.

A majority of pharmacy departments are presently conducting safety huddles within their teams.

Both researchers received $30,000 to fund projects that demonstrate the ways that new and emerging technologies can assist in the safe and effective use of medications.

The open label trial was available to patients 18 years of age and older with relapsed or refractory DLBCL after 2 or more lines of treatment.

Bezlotoxumab is administered to prevent Clostridium difficile infection from recurring in patients who are receiving treatment for the infection and are at risk for recurrence.

A pooled analysis of a 48-week open-label extension of a pair of phase 3 studies found that 99% of patients with HIV who initiated treatment using bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg tablets maintained an undetectable viral load through 4 years of follow-up.

Pembrolizumab demonstrated a statistically significant and clinically meaningful improvement in OS for patients whose tumors expressed PD-L1 with a combined positive score ≥10 compared to chemotherapy alone, according to the study.

Officials with the CDC updated their COVID-19 guidelines today, urging that vaccinated individuals in areas of substantial and high transmission wear masks in public indoor spaces, including schools, in order to prevent the spread of the Delta variant.