Gillian McGovern, Associate Editor

Compared to endocrine therapy alone, the combination of ribociclib and endocrine therapy lowered the risk of cancer recurrence in patients with early breast cancer by 25.2%.

Subcutaneous nivolumab had demonstrated noninferiority of Cavgd28, Cminss, and ORR compared to the intravenous form of treatment.

Study authors suggest that saliva samples can be a complementary testing method to provide additional information on pneumococcal carriage and serotypes that may be undetected by nasopharyngeal testing.

Study data suggest that both vaccines induce similar functional antibody responses against pneumococcal serotype 3.

The assistant program director at Mayo Clinic discusses the significance of pharmacists’ role in health care, changes throughout the industry, and her passion for mentoring pharmaceutical students.

This finding underlines the need for methods that address multiple genomic alterations and targeted therapies effective in tumors driven by variations in suppressor genes or transcription factors.

Twice-daily tenapanor tablets are recommended for patients with chronic kidney disease who are on dialysis, unresponsive or intolerant of any dose of a phosphate binder therapy.

PLCOm2012 uses additional parameters to predict the risk of lung cancer and was found more effective when identifying both Indigenous and non-Indigenous individuals with lung cancer.

According to the authors, identifying the degree of disagreement with physicians’ deprescribing recommendations can improve the communication among older adults and their physicians.

Mental health treatment may be necessary when SAEs occur.

The committee will help the FDA address issues related to digital health technologies, including artificial intelligence, virtual reality, cyber security, and patient-generated health data.

Treatment-emergent adverse events associated with Rebyota for Clostridioides difficile infection were more prevalent in those with renal comorbidities than in those without and were moderate in severity as well as related to pre-existing conditions.

The study results also indicate no significant difference of venous thromboembolism risk between individuals with immune-mediated inflammatory diseases and individuals without.

Although increased knowledge and understanding could increase uptake and acceptability of pre-exposure prophylaxis for HIV, action is needed to remove barriers and improve accessibility.

Trial data bolster the role of nivolumab and nivolumab-based combinations in both early and metastatic stages of multiple cancer types, especially in patient groups with high unmet needs.

Larger institutions have continued to treat patients who needed carboplatin or cisplatin; however, the survey results don’t include smaller cancer centers that may face access challenges.

The study authors note that it is important for expectant mothers to use antibiotics appropriately and when necessary, as well as monitor their child after birth.

Study shows that interventions may help to personalize care that meets the individual needs of patients with HIV and to improve mental health outcomes.

Study authors suggest that immunocompromised patients may greatly benefit from nirmatrelvir and ritonavir; however, there was no significant benefit shown in lower-risk patients.

Not only did the Navya-Patient Preference Tool help patients with decision-making, but groups who used the tool were more likely to receive their preferred form of surgery.

Compared with sulfonylurea, these add-on treatments were also associated with fewer diabetes-related cardiovascular and renal complications as well as avoiding hypoglycemia.

The results also indicate an association with increased risk of colorectal and noncolorectal gastrointestinal cancers as body mass index increases over time.

The manager of patient support services at St. Luke’s Cancer Center discusses the significance of Reaching Out for Healthy Women and how female patients can receive support from this initiative.

Lack of awareness, cultural beliefs, and physician preferences may influence whether minority patients receive palliative care during metastatic breast cancer treatment.

Not only did enterococci promote C. difficile pathogenesis, but it was also shown to provide fermentable amino acids, facilitating its virulence agitated gastrointestinal tracts.

The study authors suggest that after initiating alpelisib, patients should be proactive by improving glycemic status to reduce the risk of developing hyperglycemia.

Environmental factors may change sleep patterns over time, which subsequently affects rapid eye movement sleep.

The combined enfortumab vedotin-ejfv and pembrolizumab treatment is recommended for patients with locally advanced or metastatic urothelial cancer who are ineligible for cisplatin-containing therapy.

At a 6-month follow-up, supplemental creatine intervention significantly improved scores for fatigue symptoms and tissue bioenergetics related to COVID-19 infection.