CLINICAL ROLE -
Ashley Gallagher is an editor at Pharmacy Times®. She graduated from St. Bonaventure University in 2020 in journalism and mass communications. Previously, she worked as a pharmacy technician for a retail chain.
Study: New Factors Are Associated With Increased PFS from BCMA-Targeted T-Cell Therapy
A high proportion of myeloid cells may contribute to recurrence in those with long progression-free survival by promoting cancer growth and/or suppressing antitumor immunity.
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Results of New Harvard, Tufts Study Link Colorectal Cancer in Men to Ultra-Processed Foods
Processed meats and products high in added sugars and low in fiber contribute to weight gain and obesity, which is an established risk factor.
Study: Increased Use of Telehealth OUD Services During Pandemic Cuts Overdose Risk
Findings support the value of expanding this type of health care for patients with opioid use disorder.
CDC Updates ACIP Guidance, Recommending Specific Flu Vaccines for Patients 65 and Older
Flublok Quadrivalent and Fluzone High-Dose Quadrivalent are both proven to prevent more cases in older adults compared with a standard-dose vaccine in randomized controlled trials.
Janssen’s Darzalex Quadruplet for Multiple Myeloma Meets Primary Endpoint
Final analysis of phase 2 GRIFFIN study from the Johnson & Johnson subsidiary shows the combination demonstrates stringent complete response rate for transplant-eligible patients.
New Data Show Farxiga Lowers Risk of Cardiovascular Death in Patients With Heart Failure
Pre-specified pooled analysis from phase 3 trials demonstrates 14% reduction in CV mortality and from any cause by 10% in individuals with HF, irrespective of ejection fraction.
AHA: Addiction Management Is Key to Treating Heart Infections in Those Who Inject Drugs
A new statement from the American Heart Association stresses withdrawal medications and special care teams to prevent endocarditis in these individuals.
Study: Better Blood Sugar Control in Teens Limits Diabetes-Related Brain Damage
Cognitive harm appears reversible, results of analysis by Nemours Children’s Health Jacksonville and Stanford University shows.
Study: Fertility Preservation Measures Do Not Increase Risk of Breast Cancer Recurrence
Analysis shows that over 5 years, the percentage of women without relapse was 89% for those who had hormonal stimulation of the ovaries and 83% for those with ovarian tissue freezing.
Olanzapine, Samidorphan Prove Effective in Treating Bipolar 1 Disorder, Schizophrenia
Study results show that the risk of gaining 10% or more of body weight from the baseline fell 50% when patients were on the combination.
Universal Flu Vaccine Protects Against Influenza A, B Virus Variants, Study Results Show
Georgia State University analysis supports new strategy for creating these vaccines, investigators contend.
Study: Smoking Is Worse for the Heart Than Previously Thought
Some function is partially restored once smokers kick the habit, results presented at the European Society of Cardiology Congress 2022 show.
TG Therapeutics’ Ublituximab Shows Reduced Risk of Relapsing Forms of Multiple Sclerosis
Investigational targeted B-cell therapy demonstrates superior efficacy compared with teriflunomide, a commonly prescribed treatment for MS.
Study Shows Rates of Type 2 Diabetes in Children Rose During COVID-19 Pandemic
Analysis from the Johns Hopkins Children’s Center and University of Colorado indicates that cancellation of sports and a switch to virtual learning likely increased this risk.
Amgen Announces Positive Data for ABP959, Biosimilar Candidate to Soliris
Study evaluates efficacy, immunogenicity, safety of the product to eculizumab in patients with paroxysmal nocturnal hemoglobinuria.
FDA Approves Abbott’s Proclaim Plus Spinal Cord Stimulation System
Device provides tailored relief to multiple pain areas and adds more treatment options for evolving conditions.
Study: Incidence of PASC in Pediatric Individuals Is Rare
Analysis shows that myocarditis was the most commonly diagnosed condition associated with pediatric post-acute sequelae of SARS-CoV-2.
78% of Retail Pharmacists Fear Losing Patients When They Choose New Medicare Plans
Additionally, approximately 70% who responded to the EnlivenHealth survey say that one-third or more of their revenue comes from individuals eligible for the government health insurance.
Specialty Spend, Trend Report Shows AbbVie’s Humira Is Top Drug for Overall Cost
As more biosimilars and specialty generics enter the market next year, this could result in a shift in drug spending.
Pfizer, BioNTech Announce Updated COVID-19 Vaccine Efficacy Data for Young Children
Analysis is based on previously reported data collected in March and April 2022, with the FDA granting emergency use authorization for individuals aged 6 months to 4 years on June 17.
Study: Myocarditis Risk Is Significantly Higher After COVID-19 Infection Vs After Vaccine
Analysis includes nearly 43 million individuals aged 13 year and older who received at least 1 dose in England between December 1, 2020, and December 15, 2021.
Study: COVID-19 mRNA Vaccines Decrease Risk of Death for Those With Heart Failure
Results also show that no association with an increased frequency of myocarditis, venous thromboembolism, or worsening HF in these individuals.
Medical Cannabis for Chronic Pain Shows Link to Small Risk of Heart Rhythm Disorders
Danish analysis looks at the relationship between the therapy and cardiovascular adverse effects, particularly arrhythmias.
CVS Health Plans Next Steps to Expand Primary Care by End-of-Year
Executives from CVS Health said they have multiple pathways in achieving a push to establish primary care services, provider enablement, and home health.
Samidorphan/Olanzapine Combination Proves Effective in Treatment of Schizophrenia
Investigators also report that the therapy could mimic the efficacy of olanzapine but cancelled out the medication-induced weight gain, improving symptoms and outcomes.
Study: Ribavirin Forms Mutations of HEV, Causing Relapses, Treatment Failure
A P79S ORF2 variant demonstrates reduced RNA copy numbers released in the supernatant and impaired the production of infectious disease particles, investigators said.
Study Results Show COVID-19 Becomes Infectious When Symptoms are Present
Investigators report that while lateral flow tests do not detect the start of infectiousness well, they can identify individuals who will not infect others and can safely leave isolation.
Illinois Business Partners With Hospital to Reduce Readmissions
Dundee Pharmacy’s compliance packaging encourages patients to stay adherent to their medications.
FDA Accepts NDA for GSK Subsidiary’s Momelotinib for Treatment of Myelofibrosis
The regulatory submission includes data from the MOMENTUM phase 3 clinical trial that met all primary and key second efficacy end points.
Trial Results Suggest Metformin Is Effective at Reducing Odds of Serious COVID-19 Outcomes
University of Minnesota Medical School Analysis shows comparison with fluvoxamine and ivermectin in a double-blinded, placebo-controlled, randomized study.