CLINICAL ROLE -
The Expanding Role of Continuous Glucose Monitors in Pregnant Patients
The use of CGMs in pregnancy provides clinicians with essential data in real-time, rather than a snapshot given by traditional finger stick testing.
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FDA Grants Rare Pediatric Disease Designation to SAT-3247 to Treat Duchenne Muscular Dystrophy
The commencement of the phase 1 clinical trial of SAT-3247 is expected in Q3 of 2024.
Finerenone Significantly Reduces Cardiovascular Death, Heart Failure in the FINEARTS-HF Trial
Non-steroidal mineralocorticoid receptor antagonist, finerenone, demonstrated improved efficacy compared with existing steroidal treatment for patients.
FDA Declines to Approve MDMA for PTSD
Previously, an independent advisory panel for the FDA rejected the use of MDMA-assisted therapy for posttraumatic stress disorder (PTSD), citing concerns of the reliability of the clinical trial data.
Hormone Therapy May Reduce Risk of Alzheimer Disease Pathology, Cognitive Decline in Women
Findings from 2 large datasets suggest hormone therapy may reduce Alzheimer risk, hippocampal atrophy, and cerebrovascular disease.
Clinical Presentation in Patients With Lymphoma Widely Vary, Making Treatment Difficult
A variety of signs and symptoms of lymphoma were reported, including fever, stomach discomfort, and weight loss.
New Study Assesses Ifinatamab Deruxtecan for Treatment of Small Cell Lung Cancer
The study is expected to include 460 individuals that will be randomly treated with 12mg of ifinatamab deruxtecan or chemotherapy chosen by the health care provider.
New Evidence Supports Cholesterol Absorption Inhibitors in Liver Cancer Prevention
Statins and non-statin cholesterol-lowering agents show potential in reducing the risk of liver cancer.
Research Demonstrates Asthma-Related Emergency Room Visits Increase During Peak Pollen Season
A number of asthma-related emergency room visits are a result of viruses, but certain airborne pollens—notably Cupressaceae and tree pollens—are also contributors.
Experts: Pharmacists Are Accessible and Valuable Resources in Arthritis Management
A clinical pharmacy specialist and specialty pharmacy manager from Allegheny Health Network urge patients to use their pharmacist in the treatment management of arthritis.
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The Role of Pharmacists in Addressing Patient-Specific Factors and Advancing CAR T Cell Therapy
Dan Schrum discusses the integral role of pharmacy specialists in translating clinical trial results to clinical practice.
Research Identifies Key Genes Linking Hashimoto Thyroiditis and Papillary Thyroid Carcinoma
The findings may lead to the development of diagnostic and therapeutic targets to prevent worsening disease in patients.
FDA Approves First Nasal Spray for Anaphylaxis
neffy is an epinephrine nasal spray for the emergency treatment of allergic reactions in adults and pediatric patients.
ABS-0871 Receives FDA Orphan Drug Designation for Treatment of Charcot-Marie-Tooth Disease 2C
The FDA also granted rare pediatric disease designation for the drug.
Community Pharmacy’s Existential Question: Chase Product Revenue or Service Margin?
Pharmacy is at a fork in the road. Business owners, investors, and (hopefully) practicing pharmacists will have a say in which direction the profession takes
QUILT 502 Trial Will Assess N-803 With AdHER2DC Vaccine for Patients With Endometrial Cancer
Investigators will examine the combination with pembrolizumab and lenvatinib in patients with HER2-expressing endometrial cancer.
Isatuximab Shows Promise in Enhancing PFS for Patients with Multiple Myeloma
Isatuximab (Sarclisa; Sanofi) in combination with standard-of-care significantly improved progression-free survival in patients with newly diagnosed multiple myeloma.
RHB-104 Plus Standard of Care Offers Extended Treatment for Crohn Disease
The primary end point of clinical remission at week 26 was met, with 36.7% of individuals treated with RHB-104 achieving clinical remission.
Intravenous Immunoglobulin Shows Safety and Effectiveness as Treatment of Pyoderma Gangrenosum
Intravenous Immunoglobulin as a therapy for patients with pyoderma gangrenosum could open new treatment avenues for the rare and challenging condition.
Tirzepatide Meets Both Primary End Points in Phase 3 SUMMIT Trial
Tirzepatide demonstrates statistically significant improvements in adult patients who have heart failure with preserved ejection fraction and obesity.
Insights into CAR T Cell Therapy Resistance: The Impact of the Tumor Microenvironment and T Cell Exhaustion
Dan Schrum highlights the crucial role of lymphodepletion in enhancing the effectiveness of CAR T cell therapy.
FDA Grants Nalmefene Injection Approval for Emergency Treatment of Opioid Overdose
The injection adds an additional option to address emergency known or suspected opioid overdoses.
FDA Grants Accelerated Approval to Iptacopan For the Reduction of Proteinuria in Adults With IgAN
The indication is for the reduction of proteinuria in adult patients who have primary immunoglobulin A nephropathy and are at risk of disease progression.
FDA Approves Denileukin Diftitox-Cxdl for the Treatment of T-Cell Lymphoma
Denileukin diftitox-cxdl is the only therapy approved for cutaneous T-cell lymphoma that targets IL-2 receptors in malignant T-cells and Tregs.
Back-to-School Season Is Here
GLP-1 Agonists Show Promise in Treatment of Neurodegenerative Disorders
Significant commonalities between type 2 diabetes and neurodegenerative disorders suggest that treatments effective for one condition may benefit the other.
FDA Approves Carbidopa, Levodopa Extended Release for Parkinson Disease
Carbidopa and levodopa extended-release capsules are a novel, oral formulation that combine immediate-release granules and extended-release pellets.
Experts: Pharmacists Have a Crucial Role in the Treatment of Sarcomas in the Pediatric Setting
Pharmacists can personalize supportive care, educate patients and their caregivers, advocate for patients, and collaborate with other health care workers.
Study Finds Abacavir Increases Cardiovascular Risk in Patients With HIV
Cholesterol-lowering agents, like statins, reduced the risk of major adverse cardiovascular events and cardiovascular disease in patients with HIV.
Results of Study Find Irregular Sleep Patterns Associated With Diabetes Risk
The ADA Clinical Practice Recommendations added sleep assessment for precision medicine in type 2 diabetes, supporting the wealth of information surrounding the association.
