CLINICAL ROLE -
Patients With PV Who Switched from Hydroxyurea to Ruxolitinib Had Improved Hematocrit, White Blood Cell Counts
Improvements were observed regardless of whether patients initiated ruxolitinib in the second or third line of treatment.
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ASHP Midyear: Pharmacy Compounding Requires Ensuring Quality, Safety, and Preparedness
Daily operational tasks and quality assurance measures in pharmacy compounding ensures patient safety and maintains compliance.
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FDA Expands Indication for Impella Heart Pumps to Include Pediatric Patients
The pumps can now be used to treat pediatric patients who have symptomatic acute decompensated heart failure and cardiogenic shock.
Tafasitamab With Lenalidomide Plus Rituximab Improves PFS in Patients With R/R FL
Compared with placebo, patients with relapsed/refractory (R/R) follicular lymphoma (FL) who were treated with tafasitamab showed a median progression-free survival (PFS) of 22.4 months.
ASH 2024: Expert Discusses Challenges, Future Research Opportunities With Bispecific Antibodies in Multiple Myeloma
Ira Zackon, MD, explains where future research lies regarding the implementation of bispecific antibodies in community oncology settings.
SABCS 2024: Camizestrant Shows Promise in Combination with Ribociclib for Advanced Breast Cancer
The novel camizestrant-ribociclib combination demonstrated encouraging data in advanced, pre-treated ER+/HER2- breast cancer.
SABCS 2024: Unlocking the Potential of Breast Cancer Prevention Vaccines
Breast cancer prevention vaccines could have significant positive societal impact by reducing cancer diagnoses.
Navigating the Evolving Landscape of ER-Positive Metastatic Breast Cancer Treatment
Novel therapies and personalized treatment plans are improving outcomes for patients with ER-positive breast cancer.
FDA Grants Fast Track Designation to IMM-1-104 for Advanced Melanoma
Currently, the treatment is undergoing evaluation in a phase 2a trial.
Paving the Way for Better Outcomes in HER2+ Early Breast Cancer Treatment
Trastuzumab deruxtecan and trastuzumab emtansine address key challenges such as recurrence and metastases in HER2+ early breast cancer treatment.
ASHP Midyear: Pharmacists Play Key Role in Addressing Concerns and Fostering Adoption of Biosimilars
Pharmacists can help drive the successful adoption of biosimilars by developing educational programs to address provider and patient concerns.
FDA Reports Serious Liver Injury in Patients Without Cirrhosis Using Obeticholic Acid to Treat PBC
This update follows May 2021 guidelines which recommended patients with primary biliary cholangitis (PBC) with advanced cirrhosis discontinue obeticholic acid.
SABCS 2024: Combination of Elacestrant and Abemaciclib Shows Promising Progression-Free Survival in ER+/HER2- Advanced Breast Cancer
The combination of elacestrant and abemaciclib showed promising 8.7-month progression-free survival in ER+, HER2- advanced breast cancer, including in patients with ESR1 mutations.
Study: Dark Chocolate Consumption Lowers Risk of Type 2 Diabetes
Pharmacists play an essential role in educating patients about various health-related topics, including type 2 diabetes and nutrition.
ASHP Midyear: Pharmacists Play Crucial Role in Skin Care Recommendations
Pharmacists are crucial skin care experts and should counsel patients on the importance of adjunct therapies like moisturizers and sunscreen when using certain medications.
Tirzepatide Demonstrates Superiority for Weight Loss Compared With Semaglutide
The full results will be published in a peer-reviewed journal and presented at a medical meeting next year as the full results are evaluated.
Benralizumab Achieves Positive Outcomes in Eosinophilic Exacerbations in Asthma, COPD
Compared prednisolone alone, benralizumab with and without prednisolone resulted in fewer treatment failures and stronger VAS scores.
Belumosudil Commonly Used in Combination and After 3 or More Prior Lines of Therapy in Patients With cGVHD
Patients with chronic graft-versus-host disease (cGVHD) were most likely to receive belumosudil in the fourth line (33.7%) setting or the fifth through seventh line (33.1%).
SABCS 2024: Harnessing the Power of Tumor-Infiltrating Lymphocytes to Revolutionize Breast Cancer Treatment
The assessment of tumor-infiltrating lymphocytes can provide valuable insights to guide personalized treatment decisions for breast cancer patients.
The Evolution of ADCs in Breast Cancer: Challenges and Innovations
At the 2024 San Antonio Breast Cancer Symposium, experts discussed the development, clinical impact, and challenges of antibody-drug conjugates (ADCs).
SABCS 2024: Risk-Reducing Surgeries Linked to Improved Survival in Young BRCA Carriers with Breast Cancer
Both risk-reducing mastectomy and salpingo-oophorectomy were associated with significant improvements among young BRCA carriers with breast cancer.
SABCS 2024: Using Tumor Immune Profiles to Guide Neoadjuvant Therapy in Young Breast Cancer Patients
Assessing pre-treatment TIL levels in young breast cancer patients could help predict response to neoadjuvant chemotherapy.
FDA Grants Fast Track Designations to 2 Combination Influenza and COVID-19 Vaccine Candidates
The combination vaccine candidates will be evaluated in 2 separate phase 1/2 clinical trials.
Improving Patient Outcomes With Innovative Dosing and Regimen Optimization Strategies
Experts highlight the importance of dosing and regimen optimization in breast cancer to improve treatment tolerability, reduce toxicities, and improve quality of life for patients.
ASHP Midyear: Rural Health Care Barriers Impact Medication Adherence and Hypertension Management
Rural patients face significant barriers to health care access and affordability that contribute to poor hypertension management.
SABCS 2024: Imlunestrant Monotherapy and Combination with Abemaciclib Show Promising Efficacy and Safety in Metastatic Breast Cancer
Komal Jhaveri MD, FACP, shares that the combination of imlunestrant plus abemaciclib further improved progression-free survival compared to imlunestrant alone.
FDA Grants PLT012 Orphan Drug Designation for Liver, Intrahepatic Bile Duct Cancer
PLT012 demonstrates its potential against multiple tumors with unmet medical needs.
ASHP Midyear: Dose Rounding Strategies Minimize Waste and Maintain Patient Safety
Dose rounding within an acceptable range can provide cost savings and minimize waste, but requires careful interprofessional collaboration and patient education.
ASHP Midyear: High Costs of Gene Therapies Present Major Challenges to Implementation
According to the report, 75% of survey participants expect pharmacists to oversee these therapies and 58% expect Medicare will require pharmacist involvement.
SABCS 2024: The Role of ESR1 Mutation Testing and Combination Strategies in Metastatic HR+/HER2- Breast Cancer
Virginia Kaklamani, MD, DSc, shares the role of ESR1 mutation testing and combination strategies to optimize endocrine therapy in patients with metastatic HR+/HER2- breast cancer.