Assessing Adverse Events From BOVen Therapy in Patients With Previously Untreated CLL
December 21st 2021Jacob D. Soumerai, MD, of Harvard Medical School and Massachusetts General Hospital, discusses the adverse events experienced by patients with previously untreated chronic lymphocytic leukemia when treated with zanubrutinib, obinutuzumab, and venetoclax.
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Assessing Primary Endpoint Trial Results for BOVen Therapy in Previously Untreated CLL
December 20th 2021Jacob D. Soumerai, MD, of Harvard Medical School and Massachusetts General Hospital, addresses the primary endpoint in the trial assessing zanubrutinib, obinutuzumab, and venetoclax in previously untreated chronic lymphocytic leukemia.
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Assessing Zanubrutinib, Obinutuzumab, Venetoclax for Previously Untreated CLL
December 17th 2021Jacob D. Soumerai, MD, of Harvard Medical School and Massachusetts General Hospital, discusses minimum residual disease-driven time limited therapy with zanubrutinib, obinutuzumab, and venetoclax in previously untreated chronic lymphocytic leukemia.
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PI3K Inhibitors May Help Prevent Tamoxifen-Associated Uterine Cancer in Patients With Breast Cancer
December 14th 2021Uterine cancers that developed in patients with breast cancer treated with tamoxifen had fewer phosphoinositol-3-kinase (PI3K) pathway mutations and may have been driven by tamoxifen-induced PI3K pathway activation.
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Individuals With Chronic Lymphocytic Leukemia Benefit More From iFCR Therapy Than Older Individuals
December 13th 2021Matthew Davids, MD, MMSc, associate professor of medicine at Harvard Medical School, discusses how the results of a longer term study differ for individuals who were younger with chronic lymphocytic leukemia as opposed to those who are older.
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Ongoing Clinical Trials Look to Assess Optimization or Combination Treatments of Asciminib in CML
December 13th 2021Myriam Mendila, MD, chief medical officer and global head of medical affairs at Novartis Oncology, discusses ongoing trials assessing efficacy and safety of asciminib in the treatment of chronic myeloid leukemia.
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How Recent Asciminib Trial Data May Impact Treatment Strategies, Approaches for CML
December 13th 2021Myriam Mendila, MD, chief medical officer and global head of medical affairs at Novartis Oncology, discusses how the ASCEMBL study data may impact treatment strategies and approaches for patients with chronic myeloid leukemia.
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Expert Discusses Add-On Study Design for Ibrutinib as Treatment for Chronic Lymphocytic Leukemia
December 12th 2021Lindsey Roeker, MD at assistant attending L1, Memorial Sloan Kettering Cancer Center, discusses her ASH 2021 presentation and addresses the study design and the sample demographics.
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Expert Addresses Add-On Approach For the Treatment of Chronic Lymphocytic Leukemia
December 12th 2021Lindsey Roeker, MD, assistant attending L1 at Memorial Sloan Kettering Cancer Center, discusses her ASH 2021 presentation and addresses the highlights of the study and how the add-on approach affect the treatment of CLL.
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Expert Addresses How Addition of Umbralisib, Ublituximab Could Affect Treatement with Ibrutinib
December 12th 2021Lindsey Roeker, MD, assistant attending L1 at Memorial Sloan Kettering Cancer Center, discusses her ASH 2021 presentation and addresses how the addition of umbralisib and ublituximab affect those being treated with ibrutinib.
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Acalabrutinib Shows Significant Survival Benefit in Patients With Chronic Lymphocytic Leukemia
December 12th 2021The multicenter phase 3 study randomized patients with R/R CLL 1:1 to receive acalabrutinib 100 mg orally twice daily or investigator’s choice of idelalisib plus rituximab or bendamustine plus rituximab until disease progression or unacceptable toxicity.
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