CLINICAL ROLE -
January 22nd 2025
A panel of experts discuss treatment of HR+, HER2– breast cancer with therapies such as ribociclib, alpelisib, everolimus, and elacestrant.
January 21st 2025
KN026 is a humanized bispecific antibody that targets and binds to HER2 proteins on the surface of cancer cells.
January 18th 2025
Palbociclib is an oral CDK4/6 inhibitor that was approved by the FDA in 2017.
January 17th 2025
Compared with chemotherapy, Dato-DXd demonstrates favorable median progression-free survival and overall survival in a phase 3 clinical trial.
January 15th 2025
The approach favors administration of frequent low-dose chemotherapy to reduce toxicities and optimize outcomes.
FDA OKs Treatment for HER2-Negative Breast Cancer with Germline BRCA Mutation
Talazoparib is indicated for patients with known deleterious or suspected deleterious germline BRCA-mutated HER2-negative locally advanced or metastatic breast cancer.
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Sequential Regimen for HER2+ Breast Cancer Non-Inferior to Concurrent Treatment
Sequential administration of HER2+ therapy and chemotherapy did not affect survival outcomes in patients with breast cancer.