Digestive Health

Crohn disease causes inflammation of the digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.

Ulcerative colitis affects the innermost lining of your large intestine and rectum.

Irritable bowel syndrome is the term for symptoms that occur when the contents of the large intestine move too quickly or too slowly.

Symptoms of IBD include diarrhea, fatigue, abdominal pain, cramping, blood in stool, reduced appetite, and weight loss.

Recent research has linked gut microbiota and cardiovascular disease with reported differences in gut microbial compositions among individuals with and without cardiovascular disease.

IBS can be caused by muscle contractions in the intestines, nervous system, severe infections, early life stress, and changes in the gut microbes.

NAFLD is a common comorbidity for patients with IBD.

The Crohn’s disease Exclusion Diet may help to increase the food options available for many children with the condition.

The gluten-like proteins found in ryegrass could be interacting with crops commonly used as wheat replacements, which may cause a reaction among people with celiac or gluten intolerance.

Because white meat, unprocessed red meat, dairy, starch, fruit, vegetables, and legumes were not associated with the development of IBD, the way that the food is processed may confer this risk of IBD, rather than the food itself.

According to the investigators, gene changes unique among individuals who responded to mirikizumab indicate that mirikizumab affects a distinct molecular healing pathway when compared to the spontaneous healing that occurred among the cohort administered the placebo.

Study’s secondary endpoints were also met, including the achievement of endoscopic improvement, histologic-endoscopic mucosal improvement, and corticosteroid-free clinical remission at week 52.

Other options for Crohn disease and ulcerative colitis include biologics, corticosteroids, immunosuppressants, and vedolizumab.

Investigators identified 2 subgroups at risk of developing bacterial biofilms: those who have taken a significant amount of medications over their lifetimes and those who have undergone organ transplants.

Clinicians can play an important role in counseling patients about the 5 main OTC categories of laxatives to treat this gastrointestinal condition.

A combination of 2 bacteria were able to stay in the colon for an extended amount of time, rather than passing through the system quickly like other probiotics.

The approval represents the first and only oral sphingosine 1-phosphate receptor modulator indicated for adults with moderately to severely active ulcerative colitis.

The body’s relationship with gut bacteria emerges after birth and in early infancy, during important immunological and physiological development.

Eating a lot of fat and sugar damage Paneth immune cells in the small intestine, which help regulate flora.

A study published in Nature may document a previously unknown interaction between gut microbes and the thymus, an immune system organ.

When a patient recovering from gonorrhea was fed the powder of the kuchila molung plant, the patient quickly suffered from much more than painful urination.

Models without the Gastrokine-1 protein weigh less and had lower levels of total body fat, despite consuming the same amount of food.

One of the first anti-obesity therapies to be introduced and marketed as a pharmaceutical was 2-4-Dinitrophenol, which entered the market around 1934.

The study investigated whether people who regularly ate higher quantities of nitrate-rich vegetables, such as leafy greens and beetroot, had lower blood pressure.

According to the authors of the study, the findings could lead to new therapies for inflammatory bowel disease and people who've had portions of their bowels removed due to conditions such as colon cancer and ulcerative colitis.

Processed diets may initially reduce the incidence of foodborne infectious diseases, such as E.coli, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation.

If gut-imprinted immune cells are diluted in comparison to immune cells triggered by other parts of the body, there could be implications for the oral-based COVID-19 vaccines currently under development.

A greater understanding of obesity and its impact on cardiovascular health highlights abdominal obesity, sometimes referred to as visceral adipose tissue (VAT), as a cardiovascular disease risk marker.

The study authors found there were many different subtypes of goblet cells, and their functions vary more than previously thought.

Nivolumab is the first and only immunotherapy in combination with chemotherapy to deliver superior overall survival compared to chemotherapy alone in this patient population.