Specialty Pharmacy

In a new study, researchers present their findings of a signaling pathway that could be used in patients with triple-negative breast cancer (TNBC) to enhance therapies in the future.

The mitomycin gel is an alkylating drug, inhibiting the transcription of DNA into RNA and stopping protein synthesis and taking away the cancer cell’s ability to multiply.

The JAVELIN trial is a randomized, open-label, phase 3 trial comparing avelumab in combination with chemotherapy versus chemotherapy alone.

The addition of pazoparib to gemcitabine enhances anti-tumor activity, particularly for patients with platinum-resistant disease who derived the most benefit from combination therapy, even in the setting of receiving prior bevacizumab.

A new study investigated the molecular impact of the cancer-killing PARP-1 inhibitor (PARPi) binding to PARP-1 and found that the drug can be structurally modified to increase its power to kill tumor cells.

The results of this study resonate other results, suggesting that 3D mammograms are more accurate than 2D mammograms and may help 3D mammography become part of routine breast cancer screening.

Approximately 1 in 40 postmenopausal women diagnosed with breast cancer before the age of 65 had a mutation linked to cancer in the BRCA1 or BRCA2 gene, according to an analysis of data from the Women’s Health Initiative (WHI).

The kinase inhibitor selumetinib was approved for the treatment of pediatric patients aged 2 years and older with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas.

Purdue University’s College of Pharmacy is granting early graduation to 144 students to help cover a potential shortage of pharmacists during the coronavirus disease 2019 pandemic.

Although testing and vaccination for the human papillomavirus have decreased the number of cervical cancer deaths, the disease remains the fourth most common cancer type in women.

Demcizumab is a DLL4-targeted lgG2 humanized monoclonal antibody and a potent inhibitor of the Notch pathway.

COA released a statement explaining that it fundamentally opposes home infusion of chemotherapy, cancer immunotherapy, and cancer treatment supportive drugs due to concerns regarding the safety of patients in such an environment.

Every pharmacy within the Guardian Pharmacy Service network has their own disaster contingency plan in place so that they are supported in an emergency, such as the coronavirus disease 2019 pandemic.

A case study of a patient in Wuhan, China suggests that the immunosuppressant tocilizumab may be an effective coronavirus disease 2019 treatment for patients with multiple myeloma and other blood cancers.

By mining a vast trove of genetic data, researchers are enhancing physicians’ ability to treat cancer, predict patient outcomes, and determine which treatment will work best for individual patients.

FDA updates guidelines after man who recently recovered from COVID-19 was told that he could not donate blood for 12 months because he takes Truvada as a pre-exposure prophylaxis treatment.

The FDA has approved encorafenib in combination with cetuximab for the treatment of adult patients with metastatic colorectal cancer with a BRAF V600E mutation after prior therapy.

Consuming a diet high in fiber was linked with a reduced incidence of breast cancer in an evaluation of all relevant studies, according to findings published in CANCER.

Cervical cancer screening rates in Japan were significantly affected in the years following the devastating Great East Japan Earthquake of 2011, suggesting that disasters can affect cervical cancer screening for years.

Directions in Pharmacy® is a full-day regional conference for community and health-system pharmacists.

COVID-19 has caused major upheavals across the country and pharmacy schools are no exception, as many institutions have been closed, causing professors and students to seek out innovative ways to complete their coursework for the semester.

The amicus brief from the Academy of Managed Care Pharmacy argues that a ruling in favor of Rutledge would drive up health care costs and hinder patients’ ability to access affordable medications.

Eptinezumab-jjmr, the first and only intravenous treatment for migraine prevention, is now commercially available in the United States.

MDS are a group of closely related blood cancers characterized by ineffective production of healthy red blood cells, white blood cells, and platelets, which can lead to anemia and frequent or severe infections.

In a series of studies, researchers described the identification of predictive tools and a new understanding of environmental factors that trigger inflammatory bowel disease.

A new blood test has detected more than 50 types of cancer as well as their location within the body, according to an international team of researchers led by the Dana-Farber Cancer Institute and the Mayo Clinic.

New research in 5 human cancer cell lines revealed interdependencies between a tumor and its host’s microenvironment.

Pharmacists working collaboratively can make an impact, including for patients with more acute diseases.

Genomic profiles measured through circulating free DNA in the blood of patients with breast cancer may provide a more effective way to treat the disease and track its progression.

Researchers examine how stem cells promote neuronal growth in tissue regeneration and in cancer progression.