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The study met its primary endpoint of progression-free survival, and overall survival is continuing to be evaluated.

Although GLP-1 receptor agonists have shown promise in promoting weight loss, they are prescription medications and should be used under the guidance of health care professionals.

The CDK12/13 inhibitor will be tested for efficacy and safety in patients with advanced solid tumors, such as breast, ovarian, and Ewing Sarcoma.

Precision medicine in pharmacy has the potential to revolutionize patient care by optimizing drug selection, dosing, and monitoring.

Hypercortisolemia during the late afternoon and early evening is harmful and believed to cause insulin resistance observed with advanced age.

Research into the mechanisms of intravenous immunoglobulin is often challenging due to the complexity of polyclonal preparations, including diversity, repertoires, blocking, or anti-idiotypic antibodies.

A low dose of the combination treatment inhibited AML cell cycle and increased apoptosis.

Although findings indicate a relationship between vitamin D and mood disorders, further research is needed to clarify efficacy of specific vitamin D levels, as well as supplement dose and form.

Applying novel and effective behavioral economics for pre-exposure prophylaxis dissemination programs could help to tailor the programs to the populations and settings of high HIV burden areas.

In addition to improving risk evaluation in older adults at home, point-of-care testing may help clinicians manage patients with dementia who cannot communicate and those living in depopulated areas.

Harsha Rajasimha, PhD, MS, founder and CEO of Jeeva Informatics Solutions, discusses the importance of representation of women and minority groups in clinical trials.

Correctly diagnosing specific follicular lymphomas and marginal zone lymphomas requires knowledge of the clinical context, including the site of involvement, age, and clinical presentation.

Using metagenomic information, the technology isolates phages whose enzymes can specifically target the bacteria that causes C. difficile infection.

Multiple studies show that it might be more effective to administer intravenous immunoglobulins at an earlier stage of disease progression.

Investigators must find a different combination or treatment regimen using a dual blockade of the PARP and PI3K/AKT/mTOR pathway.

With the emergence of BA.2.86, and the growing prevalence of EG.5 and FL1.5.1, there is a need for updated vaccines against COVID-19 to help decrease severe disease and hospitalizations.

Patients who received amivantamab plus chemotherapy or amivantamab without chemotherapy presented better outcomes compared to chemotherapy alone.

Beyond its primary role in diabetes treatment, SGLT-2 inhibitors have demonstrated versatility in various health aspects, offering benefits beyond glucose reduction.

Black women had the highest rates of obesity-related cardiovascular disease deaths whereas other racial groups had more men experiencing obesity-related CVD deaths than women.

The importance of findability, accessibility, interoperability, and reusability has become even more significant to academics as government agencies increasingly require data openness and accessibility for funding eligibility.

Combining T and B cell vaccines could induce a strong enough immune response and protect against HIV-1 infection, although the science is not fully developed.

Crovalimab achieved disease control and non-inferiority compared to eculizumab, which is the current standard-of-care for individuals with paroxysmal nocturnal hemoglobinuria.

African ancestry was associated with higher odds of estrogen receptor-negative and triple-negative breast cancer; however, social environments were strongly associated with the survival of Black individuals with breast cancer.

Norgestrel (Opill) for pregnancy prevention will be accessible at various retail locations, including drug stores, convenience stores, grocery stores, and online platforms.

Cases of certain HPV-related high-grade disease were not found in the 10-year follow up for girls and boys who received 3 doses of the Gardasil 9 injection.

An upcoming large-scale clinical trial of the Glucose Everyday Matters program will evaluate its safety and efficacy in managing type 2 diabetes.

The upcoming study seeks to analyze whether immature lungs in infants infected with respiratory syncytial virus increases the likelihood of developing asthma later in life.

In addition to overall survival, main efficacy outcomes, such as progression-free survival, objective response rate, and time to response, were compared to chemotherapy alone.

Although antiretroviral therapies are the standard of care treatment for those with HIV, the drugs cannot target latent infections; however, venetoclax, a blood cancer treatment, shows promise.

The fixed-dose abacavir/dolutegravir/lamivudine combination is indicated for the once-daily treatment of children weighing at least 6 kg to <25 kg with HIV-1 infection.