Hospital

Glecirasib is a potent oral inhibitor of KRASG12C.

Sacituzumab govitecan improves outcomes but requires careful management of adverse effects.

Officials urge vaccinations as mobile vaccine drives ramp up to contain the outbreak.

Even for patients with myelofibrosis who could otherwise proceed directly to hematopoietic cell transplantation, pre-transplant treatment with ruxolitinib led to improved survival benefits.

Pharmacists must consider drug Interactions, allergies, and comorbidities when treating patients with urinary tract infections (UTIs).

Fred Saad, MD, discussed findings from the phase 3 ARANOTE and ARASENS trials.

Risk stratification remains a challenge when selecting patients for treatment of smoldering multiple myeloma.

Clinical pharmacists can optimize treatment through effective medication management and therapeutic drug monitoring.

New options for tirzepatide provide a transparent, out-of-pocket choice for patients by streamlining the supply chain and bypassing insurance.

Although tenofovir amibufenamide and tenofovir disoproxil fumarate (TDF) had similar effects, the former resulted in better renal safety and did not impact lipid levels.

Research has demonstrated a reduction in hospitalization risk associated with the use of LAIs, but some barriers can prevent the wider adoption of this approach.

Pembrolizumab is a humanized monoclonal antibody that targets PD-1.

The authors note that this lack of inclusion can leave important safety and efficacy questions unanswered.

Gaps in education about biosimilars, particularly among pharmacists, patients, and prescribers, are a significant barrier to wider adoption.

Tanshinlactone is an active ingredient that is commonly used in Chinese herbal medicine.

The long-term durability of response will be evaluated in the B-Sure trial (NCT04954859), which will enroll patients with hepatitis B virus (HBV) from B-Together (NCT04676724).

Curbing RSV and its complications can reduce health care costs associated with its treatment.

Melody Smith, MD, MS, discusses how microbiome modulation may influence CAR T-cell therapy toxicity and outcomes, highlighting potential future interventions and clinical integration challenges.

The approach targets cancer glucose and fatty acid metabolism, which is essential for cancer cell growth.

SkinTE could aid Wagner grade 1 diabetic foot ulcers by regenerating and activating the tissues surrounding the wound to heal it completely.

Plasma therapy can involve burdensome procedures and infusions for patients, but pharmacists can use their expertise to make the process easier and more convenient.

Using chromosome genomic array testing in combination with existing risk stratification models can better determine patients with myelofibrosis who can benefit from transplant.

The new data demonstrates the effectiveness of Mim8 in children with hemophilia A regardless of inhibitor status, expanding the populations in which the novel drug in development could have a treatment benefit.

67Cu-SAR-bisPSMA is indicated for adult patients with prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC).

Treatment with semaglutide yielded superior effects on drinking outcomes compared with existing therapies to reduce alcohol cravings.

Using central obesity measures provides more accurate estimates of the proportion of CRC cases attributable to excess weight compared to using BMI alone.

There was an association observed between fluctuating low-density lipoprotein cholesterol and the risk of developing dementia and cognitive impairment.

T-DXd has a boxed warning for interstitial lung disease and pneumonitis.

The test offers an accurate, fast, low-cost, and noninvasive tool for early diagnosis of pancreatic ductal adenocarcinoma.

Pharmacists play a vital role in supporting patients with endometriosis through guidance on treatment options and managing side effects.