Hospital

In ECOSPOR III, the lead therapeutic candidate incorporated itself durably and rapidly into the microbiome to prevent recurrence, the company says.

Evinacumab-dgnb (Evkeeza) is indicated as an adjunct to other LDL-C lowering therapies for the treatment of homozygous familial hypercholesterolemia.

Health systems must have a flexible workflow in place to allow the use of non-preferred agents to accommodate payer demands and reduce financial toxicity.

Pharmacy Times will be covering the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting live in Chicago, Illinois, from June 3 through 7, 2022.

Tisagenlecleucel was shown to be effective in high-risk patients, including those who were heavily pretreated or had refractory disease.

The FreeStyle Libre 3 is the most accurate 14-day continuous glucose monitor with a 7.9% overall mean absolute relative difference and readings are sent directly to a smartphone every minute.

Hospital pharmacists can play an instrumental role in controlling the misuse of opioids while ensuring appropriate pain management for their patients.

Nivolumab (Opdivo) with fluoropyrimidine- and platinum-containing chemotherapy and nivolumab plus ipilimumab (Yervoy) approved as first-line treatments for unresectable advanced or metastatic esophageal squamous cell carcinoma.

Voriconazole (Vfend) is an azole antifungal indicated for the treatment of invasive aspergillosis and Candidemia in non-neutropenics and other deep tissue Candida infections.

Researchers found a significant decrease in cortical silent period duration after sleep restriction in patients with interictal migraine compared to controls.

Further sensitivity analyses to control for family alcohol consumption, family history, liver disease, and smoking, finds no convincing evidence that these factors affected the results.

Research suggests that individuals receiving a vaccine, such as ones from AstraZeneca and Johnson & Johnson, were more vulnerable to infection by new variants.

Taking multiple prescription drugs and supplements can be especially dangerous for individuals with cancer who are about to undergo therapy.

When both the clinical criteria and genetic testing were combined, 6.6 familial hypercholesterolemia cases per 1000 individuals screened were found.

The use of cocaine can cause coronary artery vasospasm, which can lead to myocardial ischemia, acute coronary syndrome, and acute myocardial infarction.

Using machine learning, they find patterns in electronic health record data to help ascertain which individuals likely have the condition.

Investigators establish 2 predictive models, which had excellent performance, and included 90 children.

Treatment with nirogacestat resulted in a 71% reduction in the risk of disease progression among adults with progressing desmoid tumors.

This month's generic product news features clarithromycin, sevelamer hydrochloride, and metronidazole.

Consequences for untreated STEMI patients following the COVID-19 pandemic could include increased mortality, heart failure, and morbidities.

Immunocompromised patients are particularly at risk of developing persistent and severe anemia caused by parvovirus infections.

The approval is supported by data from a global phase 3 trial assessing the use of the drug for individuals with previously untreated IDH1-mutated acute myeloid leukemia.

Dong Xu, PhD, MS, curators' distinguished professor at the University of Missouri College of Engineering, discusses how the use of artificial intelligence may help develop new drug therapies targeting multiple disease states.

Karen Fancher, PharmD, BCOP, a member of the Patient Advisory Panel at the Hematology/Oncology Pharmacy Association (HOPA), explains how her experience as a patient with cancer and an oncology pharmacy specialist informs her work on HOPA’s Patient Advisory Panel.

The study results support a hypothesis for a differentiated mechanism from risankizumab, the company says.

This month's Rx product news features empagliflozin, mitapivat, and RSVpreF.

Sacubitril/valsartan (Entresto)reduces the risk of hospitalization and death related to cardiovascular complications in patients with heart failure.

Byron Yoshino, PharmD, CEO of Pharmacare Hawaii, discusses the future of the home infusion space within the United States in the coming years.

Sara Wettergreen, assistant professor in the department of Clinical Pharmacy, and Department of Family Medicine, at Skaggs School of Pharmacy and Pharmaceutical Sciences, on burnout and mental health concerns among pharmacy technicians

Symtuza, a 4-drug combination of darunavir (DRV), a HIV-1 protease inhibitor; cobicistat (COBI), a CYP3A inhibitor; and emtricitabine (FTC) and tenofovir alafenamide (TAF), both HIV-1 nucleoside analog reverse transcriptase inhibitors, is indicated as a complete regimen for the treatment of HIV-1 infection in patients who weigh at least 40 kg.