Granulomatosis with polyangiitis is an uncommon disorder that causes inflammation of the blood vessels in your nose, sinuses, throat, lungs, and kidneys.

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Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis.
Granulomatosis slows blood flow to some organs. The affected tissues can develop areas of inflammation called granulomas, which can affect how these organs work.
Symptoms may includepus-like drainage with crusts from the nose, stuffiness, sinus infections, nosebleeds, coughing, sometimes with bloody phlegm, shortness of breath or wheezing, fever, and joint pain.
The cause of granulomatosis with polyangiitis isn't known. It's not contagious, and there's no evidence that it's inherited.
Diagnosis may include lab tests, imaging studies, and biopsy.
Medications to treat may include corticosteroids, cyclophosphamide, azathioprine (Azasan, Imuran), mycophenolate (CellCept), methotrexate (Trexall), and rituximab (Rituxan).

Sources:

Granulomatosis with polyangiitis - Symptoms and causes - Mayo Clinic
granulomatosis image - Google Search